Finding TDC shouldn't be too hard. First you'll need a degree wheel and some type of pointer. This might be a problem if the engine is in the car, if so then you'll have to be a little less precise but you should still be able to get close. Remove the plugs and make up a piston stop from an old spark plug. I've done this by breaking out the ceramic insulator and drilling and taping the plug body for an appropriate sized bolt. Raise the piston on the number one cylinder to nearly the top, install the piston stop and adjust the bolt until it hits the piston, then lock it in position. Mark the front pully or damper at this point and then carefully turn the engine backwards until the piston hits the stop again. Mark this point. One half way between these two points is TDC. If you're using a degree wheel, then remove the piston stop, rotate the crank to where the calculated TDC lines up with the pointer and mark your damper. If you don't have the degree wheel, then measure between the two marks and mark the center. You should be close enough to be able to set the timing and tune that Prefect.
To know where the firing point is for number one, just cover the plug hole with your thumb and rotate the engine until the pressue builds on the compression stroke, the set at the TDC mark you made earlier. You should be very close to a good point for an initial static timing point.
Sorry, didn't read motorbills answer and your response fully. The piston stop will have to be somewhat different if the plug isn't over part of the piston. I'm a little surprised that it's not, as most of the flatheads I've worked on needed the clearance over the valves and moved the plug sort of in between the bore center and the valves, but usually over the edge of the piston where you could get a stop to register.
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